Fig. 3From: Herpes simplex virus-1 entrapped in Candida albicans biofilm displays decreased sensitivity to antivirals and UVA1 laser treatmentEffect of biofilm presence on virus sensitivity to antiviral drugs. Antiviral effect of 50 µM acyclovir and 600 µM foscarnet on HSV-1 infected cells embedded or not in C. albicans biofilm. Twenty-four hours old Candida biofilms were co-cultured with HSV-1-infected VERO cells in medium containing acyclovir or foscarnet. After 24 h incubation, samples were frozen and thawed to lyse infected VERO, then the released virus was end-point titrated. Controls (no biofilm) were run in parallel. *p < 0.05Back to article page