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Table 2 Comparison of biofilm production between specific gene-positive and gene-negative strains in each group

From: Investigation of biofilm production and its association with genetic and phenotypic characteristics of OM (osteomyelitis) and non-OM orthopedic Staphylococcus aureus

Strain trait

Total (n = 137)

OM (n = 60)

Non-OM (n = 77)

Adhesion-associated genes, n (%), P valuea

 bbp (+)

12 (8.8), 0.670

10 (16.7), 0.330

2 (2.6), 0.259

 cna (+)

47 (34.3), 0.223

21 (35.0), 0.670

26 (33.8), 0.036

 ebps (+)

40 (29.2), 0.558

24 (40.0), 0.214

16 (20.8), 0.552

 fib (+)

124 (90.5), 0.006

53 (88.3), 0.120

71 (92.2), 0.014

 fnbA (+)

25 (18.2), 0.737

8 (13.3), 0.433

17 (22.1), 0.810

 fnbB (+)

36 (26.3), 0.401

14 (23.3), 0.832

22 (28.6), 0.182

 icaA (+)

136 (99.3), -

59 (98.3), -

77 (100.0), -

Enterotoxin genes, n (%), P valuea

 sea (+)

11 (8.0), 0.896

7 (11.7), 0.667

4 (5.2), 0.680

 seb (+)

27 (19.7), 0.234

13 (21.7), 0.634

14 (18.2), 0.032

 sec (+)

16 (11.7), 0.104

8 (13.3), 0.083

8 (10.4), 0.558

 sed (+)

19 (13.9), 0.052

4 (6.7), 0.785

15 (19.5), 0.015

 see (+)

2 (1.5), 0.892

0 (0), -

2 (2.6), 0.860

 seg (+)

8 (5.8), 0.677

5 (8.3), 0.566

3 (3.9), 0.159

 seh (+)

4 (2.9), 0.328

0 (0), -

4 (5.2), 0.342

 sei (+)

26 (19.0), 0.004

14 (23.3), 0.002

12 (15.6), 0.311

 sej (+)

9 (6.6), 0.237

4 (6.7), 0.657

5 (6.5), 0.250

 sem (+)

29 (21.2), 0.009

15 (25.0), 0.039

14 (18.2), 0.112

 sen (+)

21 (15.3), 0.066

9 (15.0), 0.356

12 (15.6), 0.121

 seo (+)

32 (23.4), 0.002

19 (31.7), 0.005

13 (16.9), 0.123

Other toxin genes, n (%), P valuea

 hla (+)

132 (96.4), 0.074

55 (91.7), 0.073

77 (100.0), -

 hlb (+)

45 (32.8), 0.194

18 (30.0), 0.363

27 (35.1), 0.446

 hlg (+)

127 (92.7), 0.640

58 (96.7), 0.916

69 (89.6), 0.596

 hlgv (+)

127 (92.7), 0.005

55 (91.7), 0.073

72 (93.5), 0.035

 lukED (+)

90 (65.7), < 0.001

43 (71.7), 0.364

47 (61.0), < 0.001

 pvl (+)

26 (19.0), 0.319

17 (28.3), 0.589

9 (11.7), 0.419

 edin (+)

8 (5.8), 0.883

4 (6.7), 0.513

4 (5.2), 0.393

 eta (+)

5 (3.6), 0.436

2 (3.3), 0.386

3 (3.9), 0.016

 tst (+)

5 (3.6), 0.821

3 (5.0), 0.847

2 (2.6), 0.863

  1. Significant differences are in italics
  2. aBy Mann–Whitney U test, comparing biofilm production (OD492 values) between specific gene-positive and gene-negative strains in each group. Genes with carriage rate of 100% (eno,clfA,clfB,icaD,hld and psmα) or 0% (lukM and etb) were not listed