Uropathogenic bacteria | Properties | Phage | Outcome | Reference |
---|---|---|---|---|
Enterobacter cloacae | MDR | E-2, E-3 and E-4 were isolated from waste water | The growth of the bacteria was inhibited by the three phages. Notably, the use of cocktails with two or three phages was significantly more effective than each one alone. In urine, the inactivation was still effective | [65] |
Enterococcus faecalis | Clinical isolates | vB_EfaS_GEC-EfS_3 (Siphoviridae) isolated from sewage | While phage was able to infect a broad range of strains of the same species as the host species from which they were isolated, they were unable to infect other host species tested | [66] |
Enterococcus faecalis | VRE | vB_EfaS_HEf13 (genus Sap6virus in the family Siphoviridae) was collected from a local sewerage system | The lytic activity of phage HEf13 at various multiplicities of infection consistently inhibited the growth of diverse clinical isolates of E. faecalis without any lysogenic process | [67] |
Streptococcus mitis | Clinical isolates | vB_SmM_GEC-SmitisM_2 (Myoviridae) isolated from sewage | This phage was able to productively infect 9 of 16 S. mitis strains, but none of the other species in our collection | [66] |
Staphylococcus saprophyticus | MDR Clinical isolates | vB_SsapS-104 (Siphoviridae) was isolated from hospital wastewater | This phage represented high anti-bacterial activities against S. saprophyticus isolates in vitro, as it was able to lyse 8 of the 9 clinical isolates (88.8%). Notably, no lytic activity was observed on some other pathogenic bacteria tested | [68] |