Table 2 Baseline characteristics of patients with anaerobic bloodstream infections

Demographics

 Age, median (IQR)

76 (66–84)

74.9 (67.8–84.3)

74 (58–85)

77 (69–83)

83 (69–86)

 Male sex

122/215 (56.7)

33/60 (55)

31/57 (54.4)

30/52 (57.7)

14/27 (51.9)

 BMI median (IQR)

20.2 (17.8–23.0)

20.4 (18.1–22.2)

19.1 (17.3–23.0)

20.5 (17.7–23.2)

21.1 (18.0–23.3)

 Community onset

174/215 (80.9)

47/60 (78.3)

48/57 (84.2)

38/52 (73.1)

27/32 (84.3)

 Nosocomial onset

41/215 (19.1)

13/60 (21.7)

9/57 (15.8)

14/52 (26.9)

5/32 (15.6)

Comorbidities

 HIV infection

0

0

0

0

0

 ESRD on hemodialysis

13/215 (6.0)

5/60 (8.3)

2/57 (3.5)

3/52 (5.8)

1/27 (3.7)

 Diabetes mellitus

51/215 (23.7)

13/60 (21.7)

10/57 (17.5)

18/52 (34.6)

6/27 (22.2)

 Cirrhosis

4/215 (1.9)

1/60 (1.7)

1/57 (1.8)

2/52 (3.8)

1/27 (3.7)

 CHF

31/215 (14)

5/60 (8.3)

9/57 (15.8)

10/52 (19.2)

3/27 (11.1)

 COPD or severe asthma

3/215 (1.4)

0

2/57 (3.5)

1/52 (1.9)

0

 Solid tumor

62/215 (28.8)

22/60 (36.7)

14/57 (24.6)

13/52 (25)

8/27 (29.6)

 Hematological malignancy

11/215 (5.1)

3/60 (5)

2/57 (3.5)

2/52 (3.8)

1/27 (3.7)

 Alcoholism

4/215 (1.9)

0

1/57 (1.8)

1/52 (1.9)

2/27 (7.4)

 Steroid use

15/215 (7.0)

5/60 (8.3)

6/57 (10.5)

3/52 (5.8)

1/27 (3.7)

 Charlson Comordity Index, median (IQR)

5 (3–7)

5 (4–7)

5 (2–6)

5 (4–7)

5 (3–7)

Characteristics at presentation

 Fever

147/215 (68.3)

38/60 (63.3)

32/57 (56.1)

39/52 (75)

22/27 (81.5)

 Neutropenia (ANC < 1000/mL)

9/215 (4.2)

3/60 (5)

1/57 (1.8)

3/52 (5.8)

1/27 (3.7)

 Creatinine (mg/dL), median (IQR)

1.0 (0.7–1.5)

1.05 (0.74–1.62)

0.9 (0.6–1.4)

1.2 (0.8–1.8)

0.8 (0.7–1.0)

 Lactate (mmol/L), median (IQR)

2.3 (1.4–3.9)

2.4 (1.4–4.2)

2.1 (1.2–3.7)

2.6 (1.8–4.6)

2.2 (1.7–4.4)

 Central line catheter

11/215 (5.1)

3/60 (5)

5/57 (8.8)

3/52 (5.8)

0

 Urinary catheter

3/215 (1.4)

2/60 (3.3)

0

1/52 (1.9)

0

Primary source

 Oropharyngeal

14/215 (6.5)

0

4/57 (7.0)

0

8/27 (29.6)

 Pneumonia

8/215 (3.7)

0

3/57 (5.3)

1/52 (1.9)

1/27 (3.7)

 Soft tissue infection

12/215 (5.6)

3/60 (5)

6/57 (10.5)

3/52 (5.8)

0

 Central venous catheter

3/215 (1.4)

0

3/57 (5.3)

0

0

 Hepatobiliary infection

26/215 (12.1)

5/60 (8.3)

4/57 (7.0)

13/52 (25)

0

 Intra-abdominal

79/215 (36.7)

33/60 (55)

20/57 (35.1)

19/52 (36.5)

8/27 (29.6)

 Bone and joint

3/215 (1.4)

2/60 (3.3)

0

0

1/27 (3.7)

 Endocarditis

1/215 (0.5)

0

0

0

0

 Urinary tract infection

9/215 (4.2)

2/60 (3.3)

2/57 (3.5)

1/52 (1.9)

0

 Others

11/215 (5.1)

2/60 (3.3)

1/57 (1.8)

4/52 (7.7)

2/27 (7.4)

 Primary BSI

49/215 (22.8)

13/60 (21.7)

14/57 (24.6)

11/52 (21.2)

7/27 (25.9)

Bacteremia

 Polymicrobial bacteremia

92/215 (42.8)

29/60 (48.3)

26/57 (45.6)

27/52 (51.9)

15/27 (55.6)

 No. of bacteremic pathogen, median (IQR)

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

1 (1–2)

Treatment

 Portion of initial inappropriate treatment

36/208 (17.3)

17/59 (28.8)

15/55 (27.2)

5/50 (10)

5/26 (19.2)

 Surgical procedure

51/215 (23.7)

18/60 (30)

13/57 (22.8)

15/52 (28.8)

7/27 (25.9)

 ICU care

35/215 (16.3)

11/60 (18.3)

10/57 (17.5)

12/52 (23.1)

4/27 (14.8)

 Vasopressor support

43/215 (20.0)

15/60 (25)

11/57 (19.3)

15/52 (28.8)

5/27 (18.5)

 Ventilatory support

28/215 (13.0)

8/60 (13.3)

8/57 (14.0)

11/52 (21.2)

5/27 (18.5)

 Length of hospital stay, median (IQR)

20 (11–35)

27 (17–40)

18 (10–42)

21 (9–32)

16 (11–33)

 Pitt bacteremia score, median (IQR)

1 (0–3)

1.5 (0–4)

1 (0–3)

2 (1–4)

1 (0–3)

 Mortality

46/215 (21.3)

16/60 (26.7)

11/57 (19.3)

19/52 (36.5)

1/27 (3.7)