Skip to main content

Table 3 Comparison of clinical characteristics, and outcomes between surviovors and non-survivors

From: Application of MALDI-TOF MS to assess clinical characteristics, risk factors, and outcomes associated with anaerobic bloodstream infection: a retrospective observational study

Factor

Survivors (%)

Deceased (%)

p value

(n = 169)

(n = 46)

Demographics

Age, median (IQR)

75 (64–84)

81 (72–86)

0.001

 Male sex

96 (56.8)

26 (56.5)

 

 BMI, median (IQR)

19.8 (18.4–22.1)

19.8 (18.5–22.1)

 

 Community onset

140 (82.8)

34 (73.9)

 

 Nosocomial onset

29 (17.2)

12 (26.1)

 

Comorbidities

 HIV infection

0

0

 

 ESRD on hemodialysis

9 (5.3)

4 (8.7)

 

 Diabetes mellitus

34 (20.1)

17 (37.0)

0.02

 Cirrhosis

2 (1.2)

2 (4.3)

 

 CHF

22 (13.0)

9 (19.6)

 

 COPD or severe asthma

3 (1.8)

0

 

 Solid tumor

44 (26.0)

18 (39.1)

 

 Hematological malignancy

8 (4.7)

3 (6.5)

 

 Alcoholism

3 (1.8)

1 (2.2)

 

 Steroid use

9 (5.3)

6 (13.0)

 

 Charlson Comordity Index

4 (3–6)

6 (5–9)

 < 0.001

Characteristics at presentation

 Fever

125 (74.0)

22 (47.8)

 < 0.001

 Neutropenia

5 (3.0)

4 (8.7)

 

 Creatinine, median (IQR)

1.0 (0.7–1.4)

1.2 (0.8–2.0)

 

 Lactate, median (IQR)

2.2 (1.4–3.3)

3 (1.5–7.4)

0.02

 Central line catheter

9 (5.3)

2 (4.3)

 

 Urinary catheter

3 (1.8)

0

 

Primary source

 Oropharyngeal

14 (8.3)

0

0.04

 Soft tissue infection

9 (5.3)

3 (6.5)

 

 Central venous catheter

3 (1.8)

0

 

 Hepatobiliary infection

20 (11.8)

6 (13.0)

 

 Intra-abdominal

62 (36.7)

17 (37.0)

 

 Bone and joint

3 (1.8)

0

 

 Urinary tract infection

8 (4.7)

1 (2.2)

 

Bacteremia

 Polymicrobial bacteremia

70 (40.2)

22 (47.8)

 

 No. of bacteremic pathogen, median (IQR)

1 (1–2)

1 (1–2)

 

 Bacteroides spp

44 (25.3)

16 (34.8)

 

 Non-spore forming bacillis

46 (26.4)

11 (23.9)

 

 Clostridium spp

33 (19.0)

19 (41.3)

0.009

Treatment

 Initial inappropriate therapy

30 (18.5)

10 (21.7)

 

 Surgical procedure

47 (27.8)

4 (8.7)

0.04

 Vasopressor support

28 (16.6)

15 (32.6)

0.02

 Ventilatory support

20 (11.8)

8 (17.4)

 

 Length of hospital stay, median (IQR)

24 (15–35)

14 (2–30)

0.001

 Pitt bacteremia score, median (IQR)

1 (0–3)

3 (1–6)

 < 0.001

  1. Statistically significant associations are indicated in bold