Correlation of clinical sepsis definitions with microbiological characteristics in patients admitted through a sepsis alert system; a prospective cohort study

Table 2 Microbiological characteristics of the episodes (N = 514 episodes)

Characteristic	Sepsis-3 positive^a/Sepsis-2 positive (n = 341)	Sepsis-3 negative/Sepsis-2 positive (n = 70)	Sepsis-3 positive/Sepsis-2 negative (n = 16)	Sepsis-3 negative/Sepsis-2 negative (n = 87)
Microbiological findings, n (%)
BSI episodes with clinically relevant growth	124 (36.4)	21 (30.0)	6 (37.5)	7 (8.0)
Contaminated episodes	29 (8.5)	6 (8.6)	1 (6.3)	8 (9.2)
Episodes with G+ isolates	57 (16.7)	7 (10.0)	4 (25.0)	2 (2.3)
Episodes with G− isolates	79 (23.2)	14 (20.0)	2 (12.5)	4 (4.6)
Fungal isolates	1 (0.3)	0 (0.0)	0 (0.0)	0 (0.0)
Episodes with anaerobic isolates	7 (2.1)	3 (4.3)	0 (0.0)	1 (1.1)
Time to detection (h)^b	16.5 (11.6)	25.5 (22.4)	13.9 (6.0)	26.2 (13.5)

BSI blood stream infection
^aSepsis-3 positive episodes were defined as present if there was an increase in SOFA score by 2 compared to baseline, as well as evidence of infection. Infection in this study was defined as present if the patient was administered intravenous antibiotic therapy within 48 h from admission and during at least 4 days. Sepsis-2 positive episodes were defined as present if there were 2 or more SIRS criteria in combination with infection
^bDenotes mean ± standard deviation

ISSN: 1476-0711