From: Diagnostic performance of RT-PCR-based sample pooling strategy for the detection of SARS-CoV-2
Variable | Individual samples | Pooled samples | P value |
---|---|---|---|
Ct Total (n = 45)* | 28.47 (20.76–31.36) | 29.88 (23.77–33.74) | < 0.001a |
Pooling 1/10 (10%) | |||
Ct: ≤ 25 (n = 5)* | 18.46 (17.86–18.82) | 20.22 (20.02–22.26) | 0.043a |
Ct: 26–30 (n = 5)* | 29.37 (29.22–29.66) | 32.87 (31.75–33.93) | 0.042a |
Ct: 31–35 (n = 5)* | 32.15 (31.94–32.28) | 34.67 (33.67–34.81) | 0.043a |
Pooling 2/10 (20%) | |||
Ct: ≤ 25 (n = 10)* | 20.58 (17.31–21.14) | 22.68 (21.20–23.77) | 0.041a |
Ct: 26–30 (n = 10)* | 28.21 (27.56–28.44) | 28.60 (28.56–28.61) | 0.138a |
Ct: 31–35 (n = 10)* | 31.40 (31.19–32.36) | 33.74 (33.20–34.85) | 0.125a |