Microbiological diagnosis of pulmonary invasive aspergillosis in critically ill patients with severe SARS-CoV-2 pneumonia: a bronchoalveolar study

Table 2 Performance characteristics of the diagnostic tests used to diagnose CAPA

Test	TP	TN	FP	FN	S	E	PPV	NPV	LR(+)	LR(-)
EIA-GM index ≥ 0.5	35	205	11	3	92	95	76	99	18	0.08
EIA-GM index ≥ 1.0	30	213	3	8	79	99	91	96	79	0.21
AspLFD	32	230	2	6	84	99	94	97	84	0.16
Cultured on SDA	19	239	6	21	48	98	76	92	24	0.53
Calcofluor white staining	3	135	0	30	9	100	100	82	∞	0.91

Abbreviations: SDA sabouraud dextrose agar; TP true positive; TN true negative; FP false positive; FN false negative; S sensitivity; E specificity; PPV positive predictive value; NPV negative predictive value; LR(+) positive likelihood ratio; LR(-) negative likelihood ratio

ISSN: 1476-0711