Table 3 Performance characteristics of the Platelia Aspergillus galactomannan assay in BAL fluid
OD index cut-off | Parameter value (95% CI) | |||
|---|---|---|---|---|
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
≥ 0,3 | 94.7 (82.2–99.3) | 87.5 (82.3–91.6) | 57.1 (44.0-69.5) | 98.9 (96.3–99.9) |
≥ 0.5 | 92.1 (78.6–98.3) | 94.9 (91.1–97.4) | 76.1 (61.2–87.4) | 98.6 (95.8–99.7) |
≥ 1.0 | 78.9 (62.7–90.4) | 99.1 (96.7–99.9) | 93.7 (79.2–99.2) | 96.4 (93.0-98.4) |
≥ 1.5 | 65.8 (48.6–80.4) | 100 (98.3–100) | 100 (90.7–100) | 94.3 (90.5–96.9) |
≥ 2.0 | 60.5 (43.4–75.9) | 100 (98.3–100) | 100 (85.2–100) | 93.5 (89.5–96.3) |
≥ 3.0 | 50 (33.4–66.6) | 100 (98.3–100) | 100 (82.3–100) | 91.9 (87.7–95.1) |
≥ 4.0 | 15.8 (6.0-31.2) | 100 (98.3–100) | 100 (54.1–100) | 87.1 (82.3–91.0) |