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Table 2 Factors associated with Gram-negative bacterial infection among study participants

From: Multidrug-resistant Gram-negative bacterial infections and associated factors in a Kenyan intensive care unit: a cross-sectional study

 

GNB infection

cOR (95%CI)

p-value

aOR (95%CI)

p-value

Yes n(%)

No n(%)

Age

  <  = 5 years

4(4.4)

2(2.8)

0.80(0.11–6.10)

0.231

–

–

 6–17 years

3(3.3)

3(4.2)

1.60(0.23–11.27)

0.637

–

–

 18–29 years

14(15.6)

4(5.6)

0.46(0.10–2.21)

0.33

–

–

 30–41 years

19(21.1)

10(13.9)

0.84(0.22–3.26)

0.804

  

 42–53 years

27(30.0)

23(31.9)

1.36(0.39–4.75)

0.627

  

 54–65 years

15(16.7)

25(34.7)

2.67(0.74–9.67)

0.312

  

  >  = 65 years

8(8.9)

5(6.9)

Ref.

   

Gender

 Male

53(58.9)

51(70.8)

0.59(0.31–1.14)

0.139

0.51(0.24–1.09)

0.082

 Female

37(41.1)

21(29.2)

Ref.

 

Ref.

 

Pathology

 Respiratory tract conditions

16(17.8)

20(27.8)

2.5(0.96–6.50)

0.06*

5.3(1.67–16.75)

0.005**

 CVD

19(21.1)

8(11.1)

4.5(1.15–17.65)

0.031*

5.69(1.25–25.81)

0.024*

 Cancer

11(12.2)

9(12.5)

1.64(0.53–5.02)

0.389

2.63(0.7–9.92)

0.153

 Brain infection

4(4.4)

9(12.5)

1.2(0.25–5.87)

0.822

1.15(0.34–3.91)

0.819

 GIT infection

5(5.6)

3(4.2)

3.5(0.85–14.34)

0.082

1.61(0.26–10.09)

0.613

 Kidney disorder

4(4.4)

7(9.7)

1.14(0.28–4.68)

0.853

3.9(0.82–18.66)

0.088

 Fractures

7(7.8)

4(5.6)

1.11(0.56–3.22)

0.755

1.14(0.23–5.6)

0.871

 Others

24(26.7)

12(16.7)

Ref.

 

Ref.

 

Referral status

 Yes

34(37.8)

15(20.8)

2.31(1.13–4.70)

0.025*

2.15(0.87–5.33)

0.099

 No

56(62.2)

57(79.2)

Ref.

 

Ref.

 

LOS

    

 Short (≤ 5 days)

39(43.3)

37(51.4)

Ref

   

 Median (6—10 days)

31(34.4)

24(33.3)

1.73(0.73–4.086)

0.215

-

–

 Long (> 10 days)

20(22.2)

11(15.3)

1.41(0.57–3.49)

0.461

-

–

Prior antibiotics use within last 30 days

 Yes

69(76.7)

37(51.4)

3.11(1.59–6.09)

0.001**

4.23(1.77–10.11)

0.001**

 No

21(23.3)

35(48.6)

Ref.

 

Ref.

 

Invasive procedure

 Yes

67(74.4)

49(68.1)

1.37(0.69–2.71)

0.386

–

–

 No

23(25.6)

23(31.9)

Ref.

   

Prior hospitalization in the last 30 days

 Yes

56(62.2)

36(50)

1.65(0.88–3.09)

0.151

–

–

 No

34(37.8)

36(50)

Ref.

   

Using NGT

 Yes

39(43.3)

14(19.4)

3.16(1.55–6.49)

0.001**

3.04(1.26–7.32)

0.013*

 No

51(56.7)

58(80.6)

Ref.

 

Ref.

 
  1. The bolded values were the statistical significant values at P < 0.001, indicating a strong evidence against the null hypothesis
  2. ICU Intensive care unit, cOR crudes Odds Ratio, aOR adjusted Odds Ratio, LOS length of stay, RT respiratory tract, CV cardiovascular, GIT gastrointestinal tract, GNB, Gram-negative bacteria, Ref reference, CI confidence interval, NGT nasogastric tube, statistically significant at p < 0.05
  3. **statistically significant at p < 0.001