Table 3 Summary of antimicrobial susceptibility of M. abscessus complex (MABSC) based on subspecies
Drugs | N (%) of isolates | p-value | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total (N = 143) | MAB (N = 72) | MBO (N = 7) | MMA (N = 64) | ||||||||||
S | I | R | S | I | R | S | I | R | S | I | R | ||
Amikacin | 130 (90.9) | 8 (5.6) | 5 (3.5) | 59 (81.9) | 8 (11.1) | 5 (6.9) | 7 (100.0) | 0 | 0 | 64 (100.0) | 0 | 0 | 0.004 * |
Cefoxitin | 3 (2.1) | 106 (74.1) | 34 (23.8) | 1 (1.4) | 47 (65.3) | 24 (33.3) | 0 | 6 (85.7) | 1 (14.3) | 2 (3.1) | 53 (82.8) | 9 (14.1) | 0.063 |
Ciprofloxacin | 4 (2.8) | 12 (8.4) | 127 (88.8) | 1 (1.4) | 5 (6.9) | 66 (91.7) | 0 | 1 (14.3) | 6 (85.7) | 3 (4.7) | 6 (9.4) | 55 (85.9) | 0.537 |
Clarithromycin (D3) | 122 (85.3) | 1 (0.7) | 20 (14.0) | 51 (70.8) | 1 (1.4) | 20 (27.8) | 7 (100.0) | 0 | 0 | 64 (100.0) | 0 | 0 | < 0.001 * |
Doxycycline | 1 (0.7) | 11 (7.7) | 131 (91.6) | 1 (1.4) | 7 (9.7) | 64 (88.9) | 0 | 0 | 7 (100.0) | 0 | 4 (6.3) | 60 (93.8) | 0.754 |
Imipenem | 2 (1.4) | 60 (42.0) | 81 (56.6) | 1 (1.4) | 25 (34.7) | 46 (63.9) | 0 | 3 (42.9) | 4 (57.1) | 1 (1.6) | 32 (50.0) | 31 (48.4) | 0.363 |
Linezolid | 37 (25.9) | 37 (25.9) | 69 (48.3) | 17 (23.6) | 21 (29.2) | 34 (47.2) | 4 (57.1) | 2 (28.6) | 1 (14.3) | 16 (25.0) | 14 (21.9) | 34 (53.1) | 0.227 |
Moxifloxacin | 2 (1.4) | 3 (2.1) | 138 (96.5) | 2 (2.8) | 2 (2.8) | 68 (94.4) | 0 | 0 | 7 (100.0) | 0 | 1 (1.6) | 63 (98.4) | 0.707 |
TMP/SMX | 1 (0.7) | 0 | 142 (99.3) | 0 | 0 | 72 (100.0) | 0 | 0 | 7 (100.0) | 1 (1.6) | 0 | 63 (98.4) | 0.497 |
Tobramycin | 1 (0.7) | 8 (5.6) | 134 (93.7) | 1 (1.4) | 7 (9.7) | 64 (88.9) | 0 | 0 | 7 (100.0) | 0 | 1 (1.6) | 63 (98.4) | 0.172 |