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Table 5 Summary of antimicrobial susceptibility of M. abscessus complex (MABSC) based on morphotypes

From: Clinical characteristics and drug susceptibility profiles of Mycobacterium abscessus complex infection at a medical school in Thailand

Drugs

N (%) of isolates (a)

p-value

Smooth (N = 84)

Rough (N = 56)

S

I

R

S

I

R

Amikacin

82 (97.6)

2 (2.4)

0

45 (80.4)

6 (10.7)

5 (8.9)

< 0.001 *

Cefoxitin

2 (2.4)

66 (78.6)

16 (19.0)

1 (1.8)

37 (66.1)

18 (32.1)

0.172

Ciprofloxacin

3 (3.6)

9 (10.7)

72 (85.7)

1 (1.8)

3 (5.4)

52 (92.9)

0.504

Clarithromycin (D3)

78 (92.9)

1 (1.2)

5 (6.0)

41 (73.2)

0

15 (26.8)

< 0.001 *

Doxycycline

0

8 (9.5)

76 (90.5)

1 (1.8)

3 (5.4)

52 (92.9)

0.33

Imipenem

1 (1.2)

48 (57.1)

35 (41.7)

1 (1.8)

12 (21.4)

43 (76.8)

< 0.001 *

Linezolid

13 (15.5)

23 (27.4)

48 (57.1)

23 (41.1)

14 (25.0)

19 (33.9)

0.002 *

Moxifloxacin

2 (2.4)

1 (1.2)

81 (96.4)

0

2 (3.6)

54 (96.4)

0.494

TMP/SMX

1 (1.2)

0

83 (98.8)

0

0

56 (100.0)

1

Tobramycin

0

5 (6.0)

79 (94.0)

1 (1.8)

3 (5.4)

52 (92.9)

0.561

  1. * Statistically significant values
  2. (a) Three of the MAB isolates with mixed morphotypes were excluded from the analysis
  3. Abbreviations: N, number; MABSC, M. abscessus complex; S, Susceptible; I, Intermediate; R, Resistant; TMP/SMX, Trimethoprim/Sulfamethoxazole.