Table 4 Univariate and multivariate logistic regression analysis of AKI in elderly CRO patients treated with polymyxin B
Characteristic | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Odds ratio (95% confidence interval) | P-value | Odds ratio (95% confidence interval) | P-value | |
APACHE II score | 0.944 (0.897, 0.993) | 0.027 | 2.084 (1.205, 3.604) | 0.009 |
Chronic kidney disease | 7.299 (3.544, 15.034) | 0.000 | 6.705 (2.883, 15.594) | 0.000 |
Polymyxin B high dose | 1.680 (1.144–2.466) | 0.008 | ||
Duration of polymyxin B treatment (days) | 1.870 (1.302, 2.686) | 0.001 | 1.651 (1.029, 2.649) | 0.037 |
Norepinephrine dose | 1.853 (1.252, 2.743) | 0.002 | ||
Microbiological without eradication | 2.390 (1.325, 4.235) | 0.004 | 3.573 (1.779, 7.719) | 0.000 |
Clinical failure | 4.778 (2.612, 8.743) | 0.000 | ||