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Table 1 Characteristics of the investigated population

From: Negative serum (1,3) -β-D-glucan has a low power to exclude Pneumocystis jirovecii pneumonia (PJP) in HIV-uninfected patients with positive qPCR

 

PJP (n = 159)

P. jirovecii colonization (n = 54)

P value

Age (years)

59(44, 67)

62.5(48,70)

0.1803

Women (n=, %)

88(55.3)

22(40.7)

0.0827

Comorbid conditions

  

0.0227

 Hematologic malignancies (n=, %)

18 (11.3)

4 (7.4)

 Solid cancer (n=, %)

20 (12.6)

11 (20.4)

 Autoimmune or inflammatory disorders (n=, %)

77 (48.4)

23 (42.6)

 Interstitial pneumonia (n=, %)

12 (7.5)

3 (5.6)

 Nephrotic syndrome (n=, %)

22 (13.8) *

2 (3.7)

 Infectious diseases (n=, %)

7 (4.4)

7 (13.0)

 Other diseases (n=, %)

3 (1.9)

4 (7.4)

In-hospital mortality rates (n=, %)

21 (13.2)

2 (3.7)

0.0374#

Sample types

   

 Sputum (n=, %)

99 (62.3)

49 (90.7)

< 0.0001

 Bronchoalveolar lavage fluid (n=, %)

60 (37.7)

5 (9.3)

Serum BDG (pg/mL)

363.4 (174.7, 928.8)

26.45 (12.58, 61.25)

< 0.0001

  1. Mann-Whitney test was used for analysis of age and serum BDG. Fisher’s exact test was used for analysis of gender and sample types. Chi-square test was used for analysis of comorbid composition and in-hospital mortality rates (one-sided test). * The proportion of nephrotic syndrome was compared with the proportion of the combination of other comorbid between the two groups (P = 0.0465). # One sided P value. PJP: Pneumocystis jirovecii (formerly Pneumocystis carinii) pneumonia