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Table 2 Frequency and duration of antibiotics used in the linezolid and control groups

From: Effectiveness and safety of regimens containing linezolid for treatment of Mycobacterium abscessus pulmonary Disease

Regimen

Number (%)

P value

Duration* (months)

P value

Linezolid group

Control group

Linezolid group

Control group

LZD

164 (100.0)

0 (0.0)

< 0.001

15.8(15.0,16.6)

--

--

AMK

146 (89.0)

162 (94.2)

0.087

15.6(15.2,16.5)

18.1(18.0,19.0)

< 0.01

CLR/AZM

133 (81.1)

152 (88.4)

0.063

15.9(15.0,18.5)

18.0(17.8,19.0)

< 0.01

CFZ

74 (45.1)

95(55.2)

0.064

16.5(16.1,18.0)

18.0(18.0,19.0)

< 0.01

FOX

61 (37.2)

79 (45.9)

0.104

2.6(2.3,2.6)

3.0(2.5,3.0)

< 0.01

IMP

8 (4.9)

11 (6.4)

0.547

2.3(2.2,2.3)

2.6(2.5,3.0)

0.02

DOX

20(12.2)

28 (16.3)

0.275

16.5(16.2,17.0)

17.5(17.5,18.4)

< 0.01

MFX

6 (3.7)

9 (5.2)

0.485

16.9(16.0,16.73)

18.0(17.5,19.5)

< 0.01

  1. * Numbers indicate median (IQR)
  2. IQR: interquartile range; LZD, linezolid; AMK, amikacin; CLR, clarithromycin; AZM, azithromycin; CFZ, Clofazimine; FOX, cefoxitin; DOX, doxycycline; IMP, imipenem; MFX, moxifloxacin; --: no statistical value