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Table 5 Multivariate analysis of factors associated with treatment failure in patients with MAB-PD.

From: Effectiveness and safety of regimens containing linezolid for treatment of Mycobacterium abscessus pulmonary Disease

Factor

aOR

95%CI

P value

LZD

0.785

0.479–1.286

0.136

CFZ

0.785

0.479–1.286

0.944

AMK

0.864

0.378–1.977

0.730

CLR/AZM

0.829

0.437–1.570

0.565

FOX

0.598

0.374–0.956

0.033

DOX

0.971

0.594–1.588

0.759

IMP

0.965

0.502–1.260

0.840

MFX

1.294

0.791–2.119

0.108

Female

0.532

0.299–1.003

0.070

BMI ≤ 18.5 kg/m2

2.061

1.209–3.515

0.008

Age, years

   

≤ 45

1(ref)

45–65

1.285

0.813–2.574

0.356

≥65

1.430

0.799–2.559

0.138

  1. aOR: adjusted odds ratio, 95% CI: 95% confidence interval, LZD, linezolid; AMK, amikacin; CLR, clarithromycin; AZM, azithromycin; CFZ, Clofazimine; FOX, cefoxitin; DOX, doxycycline; IMP, imipenem; MFX, moxifloxacin, BMI, body mass index