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Table 1 Distribution of virulence associated genes among ESBL-EC from LRT and by ST131 affiliation

From: Molecular characterization of extended-spectrum β-lactamase-producing Escherichia coli isolated from lower respiratory tract samples between 2002 and 2019 in the Central Slovenia region

VAGsa

Total ESBL

ST131

non-ST131

Pearson Chi-Square value (df 1)

p-valueb

N = 487 (100%)

N = 329 (100%)

N = 158 (100%)

n (%)

n (%)

n (%)

Adhesins

 afa/dra

142 (29.2%)

129 (39.2%)

13 (8.2%)

49.6

 < 0.001

 fimH

450 (92.4%)

312 (94.8%)

138 (87.3%)

8.5

0.003

 iha

336 (69%)

311 (94.5%)

25 (15.8%)

309.1

 < 0.001

Autotransporters

 fluA

379 (77.8%)

291 (88.4%)

88 (55.7%)

66.4

 < 0.001

 sat

191 (39.2%)

165 (50.2%)

26 (16.5%)

50.8

 < 0.001

 vat

12 (2.5%)

0 (0%)

12 (7.6%)

25.6

 < 0.001

Protectins

 iss

38 (7.8%)

3 (0.9%)

35 (22.2%)

66.9

 < 0.001

 kpsMTII

327 (67.1%)

261 (79.3%)

66 (41.8%)

68.3

 < 0.001

 ompTAPEC

167 (34.3%)

104 (31.6%)

63 (39.9%)

3.2

 < 0.001

 traT

403 (82.8%)

288 (87.5%)

115 (72.8%)

16.3

 < 0.001

Iron acquisition systems

 fyuA

423 (86.9%)

318 (96.7%)

105 (66.5%)

85.3

 < 0.001

 iutA

414 (85%)

320 (97.3%)

94 (59.5%)

119.5

 < 0.001

Toxins

 ehxA

0 (0%)

0 (0%)

0 (0%)

  

 hlyA

32 (6.6%)

23 (7%)

9 (5.7%)

0.3

0.590

 hlyF

2 (0.4%)

0 (0%)

2 (1.3%)

3.1

0.078

 usp

347 (71.3%)

314 (95.4%)

33 (20.9%)

289.7

 < 0.001

O25b serotype

380 (78%)

313 (95.1%)

67 (42.4%)

173.1

 < 0.001

  1. aafa/dra AFA-DR family adhesins, ehxA enterohemolysin, fimH type 1-fimbrial adhesin, fluA adhesin antigen 43, fyuA yersiniabactin receptor, hlyA hemolysin A, hlyF hemolysin F, iha adhesin-siderophore, iss increased serum survival, iutA aerobactin receptor, kpsMTII group II capsule, ompTAPEC avian outer membrane protease T, sat secreted autotransporter toxin, traT transfer protein, usp uropathogenic specific protein, VAGs virulence associated genes, vat vacuolating autotransporter toxin
  2. bP-values (ST131 vs. non-ST131) calculated by Chi-square test are shown. P < 0.05 were considered statistically significant