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Table 3 Statistical analysis of pooling-based amplification

From: Integrated approach for detection of SARS-CoV-2 and its variant by utilizing LAMP and ARMS-PCR

       

Asymptotic 95% Confidence Interval

Pooling of Genes

Sensitivity

Specificity

PPV

NPV

Accuracy

Area

Lower Bound

Upper Bound

ORF1ab & N

94.78%

92.31%

95.49%

91.14%

93.87%

0.892

0.806

0.977

ORF1ab & S

93.28%

91.03%

94.70%

88.75%

92.45%

0.859

0.780

0.938

N & S

91.79%

88.46%

93.18%

86.25%

90.57%

0.777

0.670

0.884

ORF1ab, N & S

95.52%

93.59%

96.24%

92.41%

94.81%

0.882

0.782

0.982