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Table 1 Associations between the density and depth of H. pylori colonization and activity intensity of inflammation in patients with chronic gastritis (n, %)

From: Impact of Helicobacter pylori colonization density and depth on gastritis severity

Activity intensity

Overall

Treatment-naive patients

Previously treated patients

Absent

Mild

Moderate

Severe

Absent

Mild

Moderate

Severe

Absent

Mild

Moderate

Severe

The density of H. pylori colonization

 I

20 (33.9)

29 (49.2)

10 (16.9)

0 (0)

15 (31.9)

23 (48.9)

9 (19.1)

0 (0.0)

5 (41.7)

6 (50.0)

1 (8.3)

0 (0.0)

 II

38 (20.3)

79 (42.2)

65 (34.8)

5 (2.7)

31 (19.7)

66 (42.0)

55 (35.0)

5 (3.2)

7 (23.3)

13 (43.3)

10 (33.3)

0 (0.0)

 III

47 (11.5)

111 (27.1)

237 (57.9)

14 (3.4)

40 (12.0)

88 (26.5)

193 (58.1)

11 (3.3)

7 (9.1)

23 (29.9)

44 (57.1)

3 (3.9)

 IV

29 (6.2)

133 (28.6)

286 (61.5)

17 (3.7)

21 (5.6)

107 (28.8)

230 (61.8)

14 (3.8)

8 (8.6)

26 (28.0)

56 (60.2)

3 (3.2)

 χ2

NA

   

NA

   

Na

   

 P

 < 0.001

   

 < 0.001

   

0.002

   

The depth of H. pylori colonization

 I

21 (36.2)

28 (48.3)

9 (15.5)

0 (0.0)

15 (34.1)

21 (47.7)

8 (18.2)

0 (0.0)

6 (42.9)

7 (50.0)

1 (7.1)

0 (0.0)

 II

28 (20.4)

57 (41.6)

48 (35.0)

4 (2.9)

24 (20.4)

48 (41.4)

40 (34.5)

4 (3.4)

4 (19.0)

9 (42.9)

8 (38.1)

0 (0.0)

 III

85 (9.2)

267 (28.9)

541 (58.5)

32 (3.5)

68 (9.1)

215 (28.7)

439 (58.7)

26 (3.5)

17 (9.6)

52 (29.4)

102 (57.6)

6 (3.4)

 χ2

85.152

   

63.454

   

Na

   

 P

 < 0.001

   

 < 0.001

   

0.001

   
  1. NA Asymptotic method
  2. Na: Fisher’s exact test (≥ 20% T < 5 or T > 1)