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Table 3 Associations between the density and depth of H. pylori colonization and level of atrophy severity in patients with chronic gastritis (n, %)

From: Impact of Helicobacter pylori colonization density and depth on gastritis severity

Atrophy severity

Overall

   

Treatment-naive patients

Previously treated patients

Absent

Mild

Moderate

Severe

Absent

Mild

Moderate

Severe

Absent

Mild

Moderate

Severe

The density of H. pylori colonization

 I

33 (55.9)

15 (25.4)

6 (10.2)

5 (8.5)

26 (55.3)

12 (25.5)

6 (12.8)

3 (6.4)

7 (58.3)

3 (25.0)

0 (0.0)

2 (16.7)

 II

107 (57.2)

58 (31.0)

19 (10.2)

3 (1.6)

96 (61.1)

45 (28.7)

15 (9.6)

1 (0.6)

11 (36.7)

13 (43.3)

4 (13.3)

2 (6.7)

 III

271 (66.3)

106 (25.9)

29 (7.1)

3 (0.7)

223 (66.7)

83 (25.0)

24 (7.2)

29 (0.6)

48 (62.3)

23 (29.9)

5 (6.5)

1 (1.3)

 IV

308 (66.2)

137 (29.5)

17 (3.7)

3 (0.6)

250 (67.2)

109 (29.3)

11 (3.0)

2 (0.5)

58 (62.4)

28 (30.1)

6 (6.5)

1 (1.1)

 χ2

NA

   

NA

   

Na

   

 P

 < 0.001

   

 < 0.001

   

0.060

   

The depth of H. pylori colonization

 I

34 (58.6)

13 (22.4)

6 (10.3)

5 (8.5)

26 (59.1)

10 (22.7)

5 (11.4)

3 (6.8)

8 (57.1)

3 (21.4)

1 (7.1)

2 (14.3)

 II

82 (59.9)

39 (28.5)

13 (9.5)

3 (2.2)

74 (63.8)

31 (26.7)

10 (8.6)

1 (0.9)

8 (38.1)

8 (38.1)

3 (14.3)

2 (9.5)

 III

603 (65.2)

264 (28.5)

52 (5.6)

6 (0.6)

495 (66.2)

208 (27.8)

41 (5.5)

4 (0.5)

108 (61.0)

56 (31.6)

11 (6.2)

2 (1.1)

 χ2

Na

   

Na

   

Na

   

 P

0.001

   

0.017

   

0.015

   
  1. NA Asymptotic method
  2. Na: Fisher’s exact test (≥ 20% T < 5 or T > 1)