Fig. 6

Histopathological examination of liver cells. Fig a–f: Liver cells with severe degree of hydropic degeneration in all investigated groups. a: infected by S. Typhimurium ATCC 14,028, untreated, b: infected by S. Paratyphi A, untreated, c: infected by S. Typhi, untreated, d: infected by S. Typhimurium ATCC 14,028, treated by vehicle, e: infected by S. Paratyphi A, treated by vehicle, & f: infected by S. Typhi, treated by vehicle. Fig g–l: Liver cells showing mild dilation of hepatic sinusoids in all groups, some revealing adenoid pattern (g, i & j). Noticeable activation of Ito cells could be detected in all groups. While necrosis of some individual hepatocytes could be demonstrated in other groups (g, i & j) g: infected by S. Typhimurium ATCC 14,028, treated by free form, h: infected by S. Paratyphi A, treated by free form, i: infected by S. Typhi, treated by free form, j: infected by S. Typhimurium ATCC 14,028, treated by microencapsulated form, k: infected by S. Paratyphi A, treated by microencapsulated form, & l: infected by S. Typhi, treated by microencapsulated form (H&E × 400)