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Fig. 7 | Annals of Clinical Microbiology and Antimicrobials

Fig. 7

From: Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars

Fig. 7

Histopathological Examination of intestinal mucosa. a: infected by S. Typhimurium ATCC 14,028, untreated, b: infected by S. Paratyphi A, untreated, c infected by S. Typhi, untreated, d: infected by S. Typhimurium ATCC 14,028, treated by vehicle, e infected by S. Paratyphi A, treated by vehicle, & f: infected by S. Typhi, treated by vehicle. Intestinal mucosa showing marked dys-figuration of intestinal villi in all groups, marked hyperplasia of intestinal crypts in (a, d & f). The lamina propria in a, b, c, d & e showed significant number of normal essential cells of lymphocytes and macrophages, while marked depletion detected in f, g, h, i, j, k & l: Intestinal mucosa of phage treated groups showed normal criteria with some increase in the length of intestinal crypts in (j). The lamina propria harbor normal essential cell population of lymphocytes and plasma cells; in all investigated groups (H&E × 400)

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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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