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Table 3 Average body weight gain of albino mice and bacterial viable count of Salmonella serotypes in liver of animals among the groups

From: Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars

Group

Description

Average weight gain (g)

Average weight gain (%)

Mean log bacterial count in liver ± SD (CFU/g)

Group I

Uninfected, untreated

77 ± 11.5

36.3

0.0 ± 0

Group II

Infected by S. Typhimurium ATCC 14,028, untreated

29.6 ± 3

20

3.8 ± 0.36

Group III

Infected by S. Paratyphi A, untreated

19.5 ± 2.16

13.5

3.9 ± 0.26

Group IV

Infected by S. Typhi, untreated

13.7 ± 0.72

10.5

4 ± 0.15

Group V

Infected by S. Typhimurium ATCC 14,028, phage treated

38.4 ± 3.1

25.6

2.7 ± 0.26

Group VI

Infected by S. Paratyphi A, phage treated

24.3 ± 2.05

19.7

2.8 ± 0.15

Group VII

Infected by S. Typhi, phage treated

53.6 ± 3.3

34.2

2.8 ± 0.36

Group VIII

Infected by S. Typhimurium ATCC 14,028, microencapsulated phage treated

98.7 ± 5.7

49.3

2.8 ± 0.36

Group IX

Infected by S. Paratyphi A, microencapsulated phage treated

91.3 ± 4.5

46.3

2.8 ± 0.15

Group X

Infected by S. Typhi, microencapsulated phage treated

77.7 ± 8.6

40.4

2.7 ± 0.26

Group XI

Infected by S. Typhimurium ATCC 14,028, treated by vehicle

11.5 ± 1.2

7.9

3.7 ± 0.15

Group XII

Infected by S. Paratyphi A, treated by vehicle

7 ± 0.5

5.7

3.9 ± 0.26

Group XIII

Infected by S. Typhi, treated by vehicle

7 ± 0.16

6.4

3.5 ± 0.44