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Table 1 MIC values of antimicrobials for K. variicola 4253, transconjugant 4253-J53, and recipient strain J53

From: Coexistence of blaIMP−4 and blaSFO−1 in an IncHI5B plasmid harbored by tigecycline-non-susceptible Klebsiella variicola strain

 

MIC values(mg/L)

  

Antimicrobials

K. variicola 4253

4253-J53

J53

Ceftriaxone

> 128(R)

128(R)

0.06(S)

Cefotaxime

> 128(R)

128(R)

0.125(S)

Ceftazidime

> 128(R)

> 128(R)

0.5(S)

Cefepime

64(R)

32(R)

0.06(S)

Aztreonam

> 128(R)

64(R)

0.25(S)

Piperacillin/Tazobactama

> 128/4(R)

128/4(R)

4/1(S)

Amoxicillin-Clavulanic acid

> 128/64(R)

128/64(R)

4/2(S)

Imipenem

1(S)

1(S)

0.5(S)

Meropenem

1(S)

0.5(S)

0.03(S)

Fosfomycin

> 512(R)

2(S)

1(S)

Levofloxacin

0.25(S)

0.125(S)

0.06(S)

Ciprofloxacin

0.125(S)

0.008(S)

0.004(S)

Amikacin

4(S)

2(S)

2(S)

Gentamicin

128(R)

64(R)

1(S)

Trimethoprim/Sulfamethoxazole

0.25/4.75(S)

0.125/2.375(S)

0.125/0.357(S)

Tigecycline

8(R)

1(S)

0.5(S)

Colistin

0.5(S)

0.125(S)

0.125(S)

  1. R: resistant; S: susceptible
  2. aTazobactam at a fixed concentration of 4 mg/L