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Table 1 Demographic, obstetric and clinical characteristics of women with single source of pregnancy-related infection, by source of infection (n = 1,456)

From: Aetiology and use of antibiotics in pregnancy-related infections: results of the WHO Global Maternal Sepsis Study (GLOSS), 1-week inception cohort

Characteristics

Urinary tract infection

(n = 531)

Chorioamnionitis

(n = 314)

Endometritis

(n = 256)

Skin and soft tissue infection after caesarean section

(n = 180)

Abortion-related uterine infection

(n = 175)

p-value

n (%)

n (%)

n (%)

n (%)

n (%)

 

Age (years) (n = 1455)

     

0.004

 < 19

64 (12.0%)

27 (8.6%)

26 (10.2%)

8 (4.4%)

15 (8.6%)

 

 19–35

414 (78.0%)

249 (79.3%)

190 (74.2%)

145 (80.6%)

125 (71.4%)

 

 > 35

53 (10.0%)

38 (12.1%)

40 (15.6%)

27 (15.0%)

35 (20.0%)

 

Living with partner (yes -n = 1456)

430 (81.0%)

268 (85.4%)

222 (86.7%)

154 (85.6%)

117 (66.9%)

< 0.001

Schooling (years) (n = 1094)

     

0.002

 ≤ 11

195 (45.7%)

109 (44.5%)

67 (36.0%)

52 (40.6%)

65 (60.2%)

 

 > 11

232 (54.3%)

136 (55.5%)

119 (64.0%)

76 (59.4%)

43 (39.8%)

 

Country income level (n = 1456)

     

< 0.001

 Low-income

32 (6.0%)

44 (14.0%)

62 (24.2%)

57 (31.7%)

37 (21.1%)

 

 Lower-middle-income

197 (37.1%)

159 (50.6%)

110 (43.0%)

80 (44.4%)

99 (56.6%)

 

 Upper-middle-income

242 (45.6%)

60 (19.1%)

37 (14.4%)

25 (13.9%)

29 (16.6%)

 

 High-income

60 (11.3%)

51 (16.2%)

47 (18.4%)

18 (10.0%)

10 (5.7%)

 

Number of previous births (n = 1444)

     

< 0.001

 0–1

376 (71.4%)

231 (74.0%)

176 (69.8%)

131 (73.2%)

94 (54.0%)

 

 > 1

151 (28.6%)

81 (26.0%)

76 (30.2%)

48 (26.8%)

80 (46.0%)

 

Location at the time of infection suspected or confirmed (n = 1456)

    

< 0.001

 Arriving from home

314 (59.1%)

132 (42.2%)

103 (40.4%)

108 (60.3%)

104 (59.4%)

 

 Transferred from another facility

55 (10.4%)

54 (17.2%)

36 (14.1%)

11 (6.2%)

32 (18.3%)

 

 Already hospitalised

162 (30.5%)

127 (40.6%)

116 (45.5%)

60 (33.5%)

39 (22.3%)

 

Severity of infection (n = 1456)

     

< 0.001

 Less severe

447 (84.2%)

225 (71.6%)

148 (57.8%)

57 (31.7%)

33 (18.9%)

 

 Infection with complicationa

51 (9.6)

62 (19.8)

62 (24.2)

109 (60.6)

105 (60.0)

 

 Infection-related severe maternal outcomeb

33 (6.2)

27 (8.6)

46 (18)

14 (7.8)

37 (21.1)

 

Admission to intensive or high dependency care (yes, n = 1336)

56 (11.3%)

34 (12.4%)

31 (13.8%)

16 (9.6%)

14 (8.1%)

0.404

Median length of stay in intensive care unit, days (IQR)

3 (2–6)

2 (1–5)

2 (1–10)

3 (1–5)

2 (2–5)

 

Median length of stay in health facility, days (IQR)

5 (3–7)

4 (3–7)

7 (5–11)

11 (6–17)

4 (3–7)

 
  1. Data are n (%) or median (IQR: inter-quartile range); Country income according to 2018 World Bank classification
  2. aIncludes women who had an invasive procedure to treat the source of infection (vacuum aspiration, dilatation and curettage, wound debridement, drainage [incision, percutaneous, culdotomy], laparotomy and lavage, other surgery), admission to intensive care or high dependency unit, or transfer to another facility
  3. bInfection-related maternal death or near-miss. Geographical areas in six western European countries (Belgium, Denmark, Italy, Spain, the Netherlands, the UK) did not collect data for WHO near-miss criteria