Table 1 Clinical characteristics of the 107 patients with Mycobacterium avium complex pulmonary disease, classified by the presence of small colony variants
Characteristic | Total (n = 107) | Patients with coexistence of wild-type and small colony variants (n = 50) | Patients with wild-type only (n = 57) | P-value | |
|---|---|---|---|---|---|
Age (years), mean ± S.D. | 74.9 ± 10.9 | 75.8 ± 9.7 | 74.2 ± 9.7 | 0.429 | |
Female gender, n (%) | 46 (43) | 17 (34) | 29 (51) | 0.079 | |
Male gender, n (%) | 61 (57) | 33 (66) | 28 (49) | ||
Comorbidity, n (%) | Â | ||||
| Â | Previous history of tuberculosis | 5 (4.7) | 3 (6) | 2 (3.5) | 0.869 |
Bronchiectasis | 10 (9.3) | 6 (12) | 4 (7) | 0.377 | |
Chronic obstructive pulmonary disease | 20 (18.7) | 11 (22) | 9 (15.8) | 0.563 | |
Asthma | 5 (4.7) | 2 (4) | 3 (5.3) | 0.832 | |
Malignancy | 4 (3.7) | 1 (2) | 3 (5.3) | 0.498 | |
Pneumonia | 10 (9.3) | 7 (14) | 3 (5.3) | 0.411 | |
Bronchiolitis | 7 (6.5) | 2 (4) | 5 (8.8) | 0.319 | |
Hemoptysis | 8 (7.5) | 5 (10) | 3 (5.3) | 0.353 | |
Treatment initiation, n (%) | 36 (33.6) | 16 (32) | 20 (35) | 0.922 | |
Isolated species, n (%) | Â | 0.222 | |||
| Â | Mycobacterium intracellulare | 70 (65.4) | 31 (62) | 39 (68.4) | |
Mycobacterium avium subsp. hominissius | 14 (13.1) | 9 (18) | 5 (8.8) | ||
Mycobacterium avium subsp. avium | 23 (21.5) | 10 (20) | 13 (22.8) | ||